There is a link between chronically high LDL cholesterol and diabetes. Insulin resistance is associated with increased LDL, and lowered HDL cholesterol levels. Research has found that low HDL increases the risk of a cardiovascular event – such as heart attack and stroke.
Number 6. Constant Hunger
Leptin is a hormone created in adipose (fat) tissue, that is closely linked with insulin in sensing how much sugar is in the blood. When it reaches a certain level, leptin production increases to tell your brain to stop eating.
Leptin and insulin directly regulate each other. If there’s an imbalance with insulin or cells become resistant to it, leptin production can decrease and you constantly feel hungry.
Growing evidence suggests that a deficiency in leptin or low leptin sensitivity can result in the development of insulin resistance and impaired glucose metabolism.
To balance insulin and leptin, avoid inflammatory foods, and eat more anti-inflammatory foods. Watch our video, “Top 13 foods that cause inflammation”, by clicking the link above or below.
Number 5. Hypertension
If you have blood pressure readings of 130/80 or higher, you could be insulin resistant.
Insulin resistance has been repeatedly established, as a contributor to high blood pressure. When uptake of insulin is reduced, absorption of salt by the kidneys is affected, resulting in sodium overload and consequently, hypertension.
When cells are resistant to insulin, and insulin production remains at a normal rate, insulin accumulates in the blood. This condition is called hyperinsulinemia. Many studies have associated hyperinsulinemia with hypertension, although the causes may vary.
Some suggest that hypertension due to other causes lead to insulin resistance; others have found the reverse to be true. All studies agree on ONE thing – high blood pressure is an indicator of insulin resistance. When insulin sensitivity increases, the incidence and risk of hypertension decrease.
Number 4. Lethargy and Fatigue
Chronic fatigue is one of the by-products of diabetes because the body isn’t burning energy properly. With pre-diabetes, reactive hypoglycemia or blood sugar crash, can occur after a carbohydrate-rich meal. You get a surge of energy immediately after eating, insulin responds by spiking to manage the food intake, then energy crashes. This can leave you feeling sluggish and sleepy. Eating in this pattern over time, with insulin spikes and crashes, can lead to insulin resistance. Eating corn oil has been specifically shown to lead to lethargy and the development of insulin resistance. Use grass-fed butter, olive, sesame, coconut, and avocado oils instead.
Number 3. Obesity and Belly Fat
The strongest predictor of insulin resistance is obesity; this means a waistline over 40 inches in men, and 35 inches in women. Belly fat plays a part in developing chronic, or long-lasting, inflammation in the body. Chronic inflammation can damage the body over time, without any signs or symptoms. Scientists have found that complex interactions in fat tissue draw immune cells to the area, and trigger low-level chronic inflammation. This inflammation can contribute to the development of insulin resistance, type 2 diabetes, and cardiovascular disease. Studies show that losing the weight can reduce insulin resistance, and prevent or delay type 2 diabetes.
Number 2. Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS), is a disorder in which a woman’s ovaries cannot produce estrogen and progesterone normally. It is characterized by higher than normal male hormone (androgen) levels, cysts in the ovaries, and irregular or skipped periods. Studies have linked PCOS to insulin resistance in almost every case; hyperinsulinemia has been implicated as well.
Number 1. Skin Conditions
Acanthosis nigricans (AN) is a condition in which skin darkens and changes texture to a velvety feel. It most often occurs in the armpits, groin, back of the neck, between fingers and toes, and on elbows and knees. AN is associated with insulin resistance and can be either benign or malignant.
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