😱🔴Viagra may help slow how cancer spreads, scientists find…more👇💬
Researchers tested sildenafil in mouse models of breast, lung, and colon cancer, and in every case, the drug reduced the number of tumors that spread to the lungs. In the breast cancer model, sildenafil barely affected the size of the original tumor but sharply cut the number of new metastatic growths. To confirm the effect wasn’t a fluke, the team tested a related drug, vardenafil, and got the same result, then directly disabled the PDE5 gene and saw the same drop in spread — evidence pointing to that specific enzyme as the mechanism. The effect held even in mice with severely weakened immune systems, suggesting sildenafil was acting directly on the cancer cells rather than through the immune system. In lab experiments, adding a statin (lovastatin) to sildenafil reduced cancer cell movement and survival further than either drug alone, while leaving healthy, non-cancerous cells largely unaffected.
The human portion of the study drew on two decades of health records from roughly 5 million people covered by Clalit Health Services. Men who had filled at least three sildenafil prescriptions in the six months before a cancer diagnosis, and who also used statins, had a 31% lower risk of death within five years compared to men who used neither drug. To help rule out other explanations, the patient group was matched against similar non-users based on income, weight, health conditions, and cancer type, and researchers separately tested an unrelated drug, papaverine, which showed no similar benefit — supporting the idea that the effect is specific to this drug class rather than some other trait shared by Viagra users.
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