Every cell in your body requires energy to function. There are many types of energy sources available. However, glucose, which is derived from carbohydrates is of special interest within the medical community. (Updated Nov 1, 2024)
Why? Because it’s also the preferred source of energy among cancer cells. Not only do cancer cells require more glucose than healthy cells but they also metabolize it faster.
Dubbed the Warburg effect, cancer cells reprogram their metabolism to quickly and efficiently break down sugar to promote growth, survival, proliferation, and long-term maintenance.
Discovered by Nobel Prize winner, Dr. Otto Warburg found that tumors required enormous amounts of glucose compared to surrounding healthy tissue. In addition, cancer cells were also observed to be able to ferment glucose and produce lactate in the presence of oxygen, thus the term aerobic glycolysis.
Can Sugar Cause Cancer?
It seems that evidence pointing this way was discovered in a study funded by the sugar industry nearly 50 years ago — but the work was never published, until recently.
“The sugar industry did not disclose evidence of harm from animal studies that would have strengthened the case that the coronary heart disease risk of sucrose is greater than starch and caused sucrose to be scrutinized as a potential carcinogen,” the latest paper concludes. (1)
Many researchers have long pondered whether the Warburg Effect was related to how aggressively tumors grow and how cancer cells ferment sugar rather than relying on the same pathways healthy cells use to produce energy. It is this fermentation process that has now been linked to tumor growth.
According to researcher, Prof. Johan Thevelein:
“Our research reveals how the hyperactive sugar consumption of cancerous cells leads to a vicious cycle of continued stimulation of cancer development and growth. Thus, it is able to explain the correlation between the strength of the Warburg effect and tumor aggressiveness.
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